2.8 v6 does not ignite on two cylinders despite sparks

hello, I’m new here….and coming up with a problem, unfortunately my 2.8 v6 engine (174ps) makes bitches to explain….to make it short: does not ignite on cylinders 4 and 5 despite sparks ignition plugs and cables renewed, the injection nozzles of the two cylinders. also compression fits the candles of the two cylinders are wet, the engine runs extremely rough and only reluctantly takes gas, over the total speed range….what else can it be……controller, any sensor ??? k.a . if that can have something to do with it but about two weeks ago one of the two kats was removed (driver side, crumbled) someone else has a tip for me, please……