chevrolet Orlando 1,8 141 ps Bj 2011 with error P0301

Hello good evening, my buddy has n problem with his Orlando…. Engine control light on, the gas giving can be difficult on… when the accelerator pedal is fully passed it only runs on 3 cylinders…. then I have read out the error memory. Error P0301 🙁 I then renewed all spark plugs. many plug connections opened with contact spray spray spray and put together again. Refueled test drive made and still fond the asr or esp ( the lamp with the two curve n a) and the engine control light on. error memory read out, again the error p0301 cylinder 1 igniter. I don’t know why both lamps go on at the same time, I don’t know exactly what it is. but what also seems funny to me, just before the error occurred the clutch was renewed. maybe someone can help? many thanks