Ford Transit jerks under full load

Hi, I have the following problem with my transit year 2010, 2.2 Cdti, 85kw with meanwhile 320,000km: As soon as you come under full load and over 2500 rpm, you have the feeling that the engine has temporarily no full power for a few seconds. It accelerates, then takes away the power for a few seconds and then it is full again. The strange thing is that once the power is temporarily gone, the hand brake symbol lights up. If you go off the gas and drive only with half a car As or less, the performance is normal and the symbol does not shine. Brake fluid level is fine and the transit brake is also normal. MKL or the like is not on either. Thanks for the answers.